Neutrophils rarely invade dorsal root ganglia after peripheral nerve lesions
نویسندگان
چکیده
منابع مشابه
Upregulation of Ryk expression in rat dorsal root ganglia after peripheral nerve injury.
To study changes of Ryk expression in dorsal root ganglia (DRG) after peripheral nerve injury, we set up an animal model of unilateral sciatic nerve lesioned rats. Changes of Ryk protein expression in DRG neurons after unilateral sciatic nerve injury were investigated by immunostaining. Changes of Ryk mRNA were also tested by semi-quantitative PCR concurrently. We found, both at the level of pr...
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The evidence of neurons generated ex novo in sensory ganglia of adult animals is still debated. In the present study, we investigated, using high resolution light microscopy and stereological analysis, the changes in the number of neurons in dorsal root ganglia after 30 days from a crush lesion of the rat brachial plexus terminal branches. Results showed, as expected, a relevant hypertrophy of ...
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The presence of microglia in dorsal root ganglia (DRG) has not been reported earlier. The dorsal root ganglia contain satellite glial cells (SGCs) and macrophages, which are considered to have infiltrated from the systemic blood. An attempt was made to investigate whether microglia as found in the central nervous system are also present in the dorsal root ganglia of untreated rats and following...
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Immunohistochemical studies with monoclonal antibodies to macrophage antigens were performed on sections of rat lumbar dorsal root ganglia. In confirmation of previous observations, cells with macrophage antigenicity were detected in normal ganglia. Many of these presumptive macrophages were perineuronal in contact with the neuron/satellite cell complex, a few were perivascular, and others were...
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IN DORSAL ROOT GANGLIA AND PERIPHERAL NERVE OF THE RAT AND OTHER SPECIES, NUCLEOSIDE PHOSPHATASE AND UNSPECIFIC CHOLINESTERASE REACTION PRODUCTS ARE FOUND IN THE PLASMA MEMBRANES AND SPACES BETWEEN THEM AT TWO SITES: (1) Schwann cell-axon interfaces and mesaxons of unmyelinated fibers, and (2) sheath cell-perikaryon interfaces and interfaces between adjacent sheath cells. Acetylcholinesterase r...
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ژورنال
عنوان ژورنال: Journal of Neuroimmunology
سال: 2007
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2007.05.001